Mayo Clinic
Tirzepatide contraindications and side effects for pharmaceutical grade medication.
Procedural Aspiration Risks for GLP-1 patients
Concerns of GLP-1 agonists-induced delayed gastric emptying and associated high risk of regurgitation and aspiration of gastric contents, the task force suggests the following for elective procedures. For patients requiring urgent or emergent procedures, proceed and treat the patient as ‘full stomach’ and manage accordingly.
For patients scheduled for elective procedures consider the following:
Day(s) Prior to the Procedure:
For patients on daily dosing consider holding GLP-1 agonists on the day of the procedure/surgery. For patients on weekly dosing consider holding GLP-1 agonists a week prior to the procedure/surgery.
American Society of Anesthesiologists
Tirzepatide Surmount Study
Continued Treatment With Tirzepatide for Maintenance of Weight Reduction in Adults With Obesity: The SURMOUNT-4 Randomized Clinical Trial
Dual Agonist (GIP and GLP-1)/ Twincretin Surpass and Surmount studies
The evaluation of the Surmount and Suprass studies deduces that there are cardiovascular benefits and reduced need for insulin during dual agonist Tirzepatide research studies.